Levaquin

Brand: LEVAQUIN

Generic: LEVOFLOXACINE

LEVAQUIN is a broad-spectrum quinolone antibiotic used in adults to treat lung, sinus, skin, and urinary tract infections caused by certain germs called bacteria.

►Respiratory Infections:

• Acute bacterial sinusitis
• Acute bacterial exacerbation of chronic bronchitis
• Pneumonia
  • Hospital-acquired (nosocomial)
  • Community-acquired

►Skin Infections:

• Complicated skin and skin structure infections
• Uncomplicated skin and skin structure infections

►Kidney & Urinary Tract Infections

• Chronic bacterial prostatitis
• Complicated urinary tract infections
• Acute pyelonephritis
• Uncomplicated urinary tract infections

LEVAQUIN GENERIC (origin: India) 30 tablets 500MG: $ 90.00
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PATIENT INFORMATION

  Levaquin Patient Information (41.7 KiB, 43 hits)

MEDICATION GUIDE

  Levaquin Prescribing Information (173.2 KiB, 34 hits)

SAFETY INFORMATION

►The most important information about LEVAQUIN

LEVAQUIN belongs to a class of antibiotics called fluoroquinolones. LEVAQUIN can cause side effects that may be serious or even cause death. If you get any of the following  serious side effects, get medical help right away. Talk with your healthcare provider about whether you should continue to take LEVAQUIN.

• Tendon rupture or swelling of the tendon (tendinitis)
  • Tendons are tough cords of tissue that connect muscles to bones.
  • Pain, swelling, tears, and inflammation of tendons including the back of the ankle (Achilles), shoulder, hand, or other tendon sites can happen in people of all ages who take fluoroquinolone antibiotics, including LEVAQUIN. The risk of getting tendon problems is higher if you:
    • are over 60 years of age
    • are taking steroids (corticosteroids)
    • have had a kidney, heart or lung transplant.
    • swelling of the tendon (tendinitis) and tendon rupture (breakage) have also happened in patients who take fluoroquinolones who do not have the above risk factors.
  • Other reasons for tendon ruptures can include:
    • physical activity or exercise
    • kidney failure
    • tendon problems in the past, such as in people with rheumatoid arthritis (RA).
  • Call your healthcare provider right away at the first sign of tendon pain, swelling or inflammation. Stop taking LEVAQUIN until tendinitis or tendon rupture has been ruled out by your healthcare provider. Avoid exercise and using the affected area. The most common area of pain and swelling is the Achilles tendon at the back of your ankle. This can also happen with other tendons. Talk to your healthcare provider about the risk of tendon rupture with continued use of LEVAQUIN. You may need a different antibiotic that is not a fluoroquinolone to treat your infection.
  • Tendon rupture can happen while you are taking or after you have finished taking LEVAQUIN. Tendon ruptures have happened up to several months after patients have finished taking their fluoroquinolone.
  • Get medical help right away if you get any of the following signs or symptoms of a tendon rupture:
    • hear or feel a snap or pop in a tendon area
    • bruising right after an injury in a tendon area
    • unable to move the affected area or bear weight

►Do not take LEVAQUIN if:

• you have ever had a severe allergic reaction to an antibiotic known as a fluoroquinolone
• you are allergic to any of the ingredients in LEVAQUIN (active ingredient: levofloxacin)

►Before taking LEVAQUIN, tell your healthcare provider about all your medical conditions, including if you:

• have tendon problems
• have central nervous system problems (such as epilepsy)
• have nerve problems
• have or anyone in your family has an irregular heartbeat, especially a condition called “QT prolongation.”
• have low blood potassium (hypokalemia)
• have a history of seizures
• have bone and joint problems
• have kidney problems. You may need a lower dose of LEVAQUIN if your kidneys do not work well.
• have liver problems
• have rheumatoid arthritis (RA) or other history of joint problems
• are pregnant or planning to become pregnant. It is not known if LEVAQUINwill harm your unborn child.
• are breast-feeding or planning to breast-feed. LEVAQUIN is thought to pass into breast milk. You and your healthcare provider should decide whether you will take LEVAQUIN or breast-feed.

►If you have been prescribed LEVAQUIN after being exposed to anthrax:

• LEVAQUIN has been approved to lessen the chance of getting anthrax disease or worsening of the disease after you are exposed to the anthrax bacteria germ.
• Take LEVAQUINexactly as prescribed by your healthcare provider. Do not stop taking LEVAQUIN without talking with your healthcare provider. If you stop taking LEVAQUIN too soon, it may not keep you from getting the anthrax disease.
• Side effects may happen while you are taking LEVAQUIN. When taking LEVAQUINto prevent anthrax infection, you and your healthcare provider should talk about whether the risks of stopping your medicine too soon are more important than the risks of side effects with LEVAQUIN. It is not known if it is safe to use LEVAQUINfor more than 28 days in adults and for more than 14 days in children 6 months of age and older.
• If you are pregnant, or plan to become pregnant while taking LEVAQUIN, you and your healthcare provider should decide whether the benefits of taking LEVAQUIN for anthrax are more important than the risks.

►What to avoid while taking LEVAQUIN?

• LEVAQUINcan make you feel dizzy and lightheaded. Do not drive, operate machinery, or do other activities that require mental alertness or coordination until you know how LEVAQUIN affects you.
• Avoid sunlamps, tanning beds, and try to limit your time in the sun. LEVAQUIN can make your skin sensitive to the sun (photosensitivity) and the light from sunlamps and tanning beds. You could get severe sunburn, blisters or swelling of your skin. If you get any of these symptoms while taking LEVAQUIN, call your healthcare provider right away. You should use a sunscreen and wear a hat and clothes that cover your skin if you have to be in sunlight.

POSSIBLE SIDE EFFECTS

LEVAQUIN can cause side effects that may be serious or even cause death. See “The most important information about LEVAQUIN”)

►OTHER SIDE EFFECTS:

• Liver damage (hepatotoxicity): Liver damage (hepatotoxicity) can happen in people who take LEVAQUIN. Call your healthcare provider right away if you have unexplained symptoms such as:
  • nausea or vomiting
  • stomach pain
  • fever
  • weakness
  • abdominal pain or tenderness,
  • itching
  • unusual tiredness
  • loss of appetite
  • light colored bowel movements
  • dark colored urine or yellowing of your skin or the whites of your eyes.

• Central Nervous System Effects. Seizures have been reported in people who take fluoroquinolone antibiotics including LEVAQUIN. Tell your healthcare provider if you have a history of seizures. Ask your healthcare provider whether taking LEVAQUIN will change your risk of having a seizure. Central Nervous System (CNS) side effects may happen as soon as after taking the first dose of LEVAQUIN. Talk to your healthcare provider right away if you get any of these side effects, or other changes in mood or behavior:
  • seizures
  • hear voices, see things, or sense things that are not there (hallucinations)
  • feel restless
  • tremors
  • feel anxious or nervous
  • confusion
  • depression
  • trouble sleeping
  • nightmares
  • feel lightheaded
  • feel more suspicious (paranoia)
  • suicidal thoughts or acts

• Serious allergic reactions. Allergic reactions can happen in people taking fluoroquinolones, including LEVAQUIN, even after only one dose. Stop taking LEVAQUIN and get emergency medical help right away if you get any of the following symptoms of a severe allergic reaction:

• • hives
  • trouble breathing or swallowing
  • swelling of the lips, tongue, face
  • throat tightness, hoarseness
  • rapid heartbeat
  • faint
  • Yellowing of the skin or eyes. Stop taking LEVAQUIN and tell your healthcare provider right away if you get yellowing of your skin or white part of your eyes, or if you have dark urine. These can be signs of a serious reaction to LEVAQUIN(a liver problem).

• Skin rash. Skin rash may happen in people taking LEVAQUIN, even after only one dose. Stop taking LEVAQUINat the first sign of a skin rash and call your healthcare provider. Skin rash may be a sign of a more serious reaction to LEVAQUIN.

• Intestine infection (Pseudomembranous colitis). Pseudomembranous colitis can happen with most antibiotics, including LEVAQUIN. Call your healthcare provider right away if you get watery diarrhea, diarrhea that does not go away, or bloody stools. You may have stomach cramps and a fever. Pseudomembranous colitis can happen 2 or more months after you have finished your antibiotic.

• Changes in sensation and possible nerve damage (Peripheral Neuropathy). Damage to the nerves in arms, hands, legs, or feet can happen in people taking fluoroquinolones, including LEVAQUIN. Talk with your healthcare provider right away if you get any of the following symptoms of peripheral neuropathy in your arms, hands, legs, or feet:
  • pain
  • burning
  • tingling
  • numbness
  • weakness

  LEVAQUIN may need to be stopped to prevent permanent nerve damage.

• Serious heart rhythm changes (QT prolongation and torsades de pointes). Tell your healthcare provider right away if you have a change in your heart beat (a fast or irregular heartbeat), or if you faint. LEVAQUINmay cause a rare heart problem known as prolongation of the QT interval. This condition can cause an abnormal heartbeat and can be very dangerous. The chances of this happening are higher in people:
  • who are elderly
  • with a family history of prolonged QT interval
  • with low blood potassium (hypokalemia)
  • who take certain medicines to control heart rhythM (antiarrhythmics)

• Changes in blood sugar [low blood sugar (hypoglycemia) and high blood sugar (hyperglycemia)]. People who take LEVAQUIN and other fluoroquinolone medicines with oral anti-diabetes medicines or with insulin can get low blood sugar (hypoglycemia) and high blood sugar (hyperglycemia). Follow your healthcare provider’s instructions for how often to check your blood sugar. If you have diabetes and you get low blood sugar while taking LEVAQUIN, stop taking LEVAQUIN and call your healthcare provider right away. Your antibiotic medicine may need to be changed.

• Sensitivity to sunlight (photosensitivity)

• Joint Problems. Increased chance of problems with joints and tissues around joints in children. Tell your child’s healthcare provider if your child has any joint problems during or after treatment with LEVAQUIN.

►MOST COMMON SIDE EFFECTS:

• dizziness
• headache
• constipation
• nausea
• diarrhea

In children 6 months and older who take LEVAQUIN to prevent anthrax disease, vomiting is also common.

Low blood pressure can happen with LEVAQUINgiven by IV injection if it is given too fast. Tell your healthcare provider if you feel dizzy, or faint during a treatment with LEVAQUIN.

LEVAQUIN may cause false-positive urine screening results for opiates when testing is done with some commercially available kits. A positive result should be confirmed using a more specific test.

These are not all the possible side effects of LEVAQUIN. Tell your healthcare provider about any side effect that bothers you or that does not go away.

DRUG INTERACTION

Tell your healthcare provider about all the medicines youtake, including prescription and non-prescription medicines, vitamins, herbal and dietary supplements. LEVAQUIN and other medicines can affect each other causing side effects.

Especially tell your healthcare provider if you take:

• an NSAID (Non-Steroidal Anti-Inflammatory Drug). Many common medicines for pain relief are NSAIDs. Taking an NSAID while you take LEVAQUIN or other fluoroquinolones may increase your risk of central nervous system effects and seizures.
• an oral anti-diabetes medicine or insulin
• a blood thinner (warfarin, Coumadin, Jantoven)
• a medicine to control your heart rate or rhythm (antiarrhythmics).
• an anti-psychotic medicine
• a tricyclic antidepressant
• a water pill (diuretic)
• a steroid medicine. Corticosteroids taken by mouth or byinjection may increase the chance of tendon injury
• theophylline (Theo-24®, Elixophyllin®, Theochron®, Uniphyl®, Theolair®)

Certain medicines may keep LEVAQUIN from workingc orrectly. Take LEVAQUIN Tablets or Oral Solution either 2 hours before or 2 hours after taking these products:

• an antacid, multivitamin, or other product that has magnesium, aluminum, iron, or zinc.
• sucralfate (Carafate®)
• didanosine (Videx®, Videx®EC)