Axert

Brand: AXERT

Generic: ALMOTRIPTAN

AXERT is a medication used to treat migraine attacks in adults and adolescents age 12 to 17 years.

AXERT is a member of a class of drugs called selective serotonin receptor agonists.

Use AXERT only for a migraine attack.

AXERT BRAND (Ortho-McNeil) (origin: France) 6 tablets 12.5MG:  $ 60.00
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MEDICATION GUIDELINES

  Axert Prescribing Information (203.7 KiB, 32 hits)

SAFETY INFORMATION

►Do not take AXERT if:

• have ever had heart disease.
• have uncontrolled high blood pressure.
• have hemiplegic or basilar migraine. If you are not sure, ask your doctor.
• have taken another serotonin receptor agonist (e.g. another triptan) in the last 24 hours. These include naratriptan (AMERGE®), rizatriptan (MAXALT®), sumatriptan (IMITREX®, TREXIMET®), or zolmitriptan (ZOMIG®).
• have taken ergotamine-type medicines in the last 24 hours.  These include ergotamine (BELLERGAL-S®, CAFERGOT®, ERGOMAR®, WIGRAINE®), dihydroergotamine (D.H.E. 45®), or methysergide (SANSERT®).
• had an allergic reaction to AXERT or any of its ingredients. The active ingredient is almotriptan malate. Ask your doctor or pharmacist about inactive ingredients.

►Before taking AXERT, tell your doctor:

• about any past or present medical problems.
• about any past or present high blood pressure, chest pain, shortness of breath, or heart disease.
• about any liver or kidney problems.
• about any risk factors for heart disease, such as:
  • high blood pressure
  • diabetes
  • high cholesterol
  • overweight
  • smoking
  • family members with heart disease
  • you are past menopause
  • if you are a male over 40 years old.
  • if you are allergic reactions to sulfonamides, also known as sulfa drugs (ask your doctor if you are not sure what sulfonamide drugs are).
  • about medicines you take or plan to take, including prescription and non-prescription medicines and herbal supplements. Be sure to include medicines you normally take for a migraine.
  • if you are pregnant or planning to become pregnant
  • if you are breast-feeding or planning to.

►What to avoid while taking AXERT:

Check with your doctor before you take any new medicines, including prescription and non-prescription medicines and supplements. There are some medicines that you should not take during the period 24 hours before and 24 hours after taking AXERT.

POSSIBLE SIDE EFFECTS

► MOST COMMON SIDE EFFECTS IN ADULTS

• Sleepiness
• Tingling or burning feeling (paresthesia)
• Headache
• Dry mouth

► MOST COMMON SIDE EFFECTS IN ADOLESCENTS

• Dizziness
• Sleepiness
• Nausea
• Headache
• Tingling or burning feeling (paresthesia)
• Vomiting

The side effects are usually mild and do not last long.

If you experience sleepiness, you should evaluate your ability to perform complex tasks such as driving or operating heavy machinery.

► ALLERGIC REACTION

Tell your doctor if you develop a  rash or itching after taking AXERT. You may be allergic to the  medicine.

► VERY RARE SIDE EFFECTS

In very rare cases, patients taking this class of medicines  experience serious heart problems, stroke, or increased blood  pressure. Extremely rarely, patients have died.  Therefore, tell your doctor right away if you feel tightness, pain,  pressure, or heaviness in your chest, throat, neck, or jaw after  taking AXERT. Do not take AXERT again until your doctor has  checked you.

►SEROTONIN SYNDROME

Some people may have a reaction called serotonin syndrome,  which can be life-threatening, when they use AXERT. In particular,  this reaction may occur when they use AXERT together with  certain types of antidepressants known as SSRIs or SNRIs.  Symptoms may include mental changes (hallucinations,  agitation, coma), fast heartbeat, changes in blood pressure, high  body temperature or sweating, tight muscles, trouble walking,  nausea, vomiting, diarrhea. Call your doctor immediately if you  have any of these symptoms after taking AXERT.

This is not a complete list of side effects. Talk to your doctor if you develop any symptoms that concern you.

INGREDIENTS

Active ingredient:

• almotriptan malate

Inactive ingredients:

• mannitol, cellulose, povidone, sodium starch glycolate, sodium stearyl fumarate, titanium dioxide, hypromellose, polyethylene glycol, propylene glycol, iFD&C Blue No. 2 (12.5 mg only), and carnauba wax.

DRUG INTERACTION

These medicines may affect how AXERT works, or AXERT mayaffect how these medicines work. Tell your doctor if you take:

• monoamine oxidase (MAO) inhibitors, such as phenelzine sulfate (NARDIL®) or tranylcypromine sulfate (PARNATE®) for depression or another condition, or if it has been less than two weeks since you stopped taking an MAO inhibitor.
• ketoconazole (NIZORAL®), itraconazole (SPORANOX®), ritonavir (NORVIR®), or erythromycin (EMYCIN®), or if it has been less than one week since you stopped taking one of these drugs.
• selective serotonin reuptake inhibitors (SSRIs) or serotonin norepinephrine reuptake inhibitors (SNRIs), two types of drugs for depression or other disorders. Common SSRIs are CELEXA® (citalopram HBr), LEXAPRO® (escitalopram oxalate), PAXIL® (paroxetine), PROZAC®/SARAFEM® (fluoxetine), SYMBYAX® (olanzapine/fluoxetine), ZOLOFT® (sertraline), and fluvoxamine. Common SNRIs are CYMBALTA® (duloxetine) and EFFEXOR® (venlafaxine).

Also tell your doctor about any other medicines you take, including prescription and non-prescription medicines, vitamins, and herbal supplements.